Clipsin, a chymotrypsin-like protease in rat brain which is irreversibly inhibited by α-1-antichymotrypsinNELSON, R. B; SIMAN, R.The Journal of biological chemistry (Print). 1990, Vol 265, Num 7, pp 3836-3843, issn 0021-9258, 8 p.Article

Excitatory amino acid neurotoxicity in the hippocampal slice preparationSIMAN, R; CARD, J. P.Neuroscience. 1988, Vol 26, Num 2, pp 433-447, issn 0306-4522Article

β-amyloid precursor is a PEST proteinSIMAN, R; CHRISTOPH, G.Biochemical and biophysical research communications (Print). 1989, Vol 165, Num 3, pp 1299-1304, issn 0006-291XArticle

Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brainSIMAN, R; SALIDAS, S.Neuroscience. 2004, Vol 129, Num 3, pp 615-628, issn 0306-4522, 14 p.Article

Identification and characterization of calcium-dependent metalloproteases in rat brainNELSON, R. B; SIMAN, R.Journal of neurochemistry. 1989, Vol 53, Num 2, pp 641-647, issn 0022-3042Article

Clipsin, a chymotrypsin-like protease in rat brain which is irreversibly inhibited by α-1 antichymptrypsinNELSON, R. B; SIMAN, R.The Journal of biological chemistry (Print). 1991, Vol 266, Num 19, issn 0021-9258, p. 12796Article

Immunolocalization of caspase proteolysis in situ : Evidence for widespread caspase-mediated apoptosis of neurons and glia in the postnatal rat brainSIMAN, R; BOZYCZKO-COYNE, D; MEYER, S. L et al.Neuroscience. 1999, Vol 92, Num 4, pp 1425-1442, issn 0306-4522Article

APP Transgenesis : Approaches toward the development of animal models for Alzheimer disease neuropathologyGREENBERG, B. D; SAVAGE, M. J; HOWLAND, D. S et al.Neurobiology of aging. 1996, Vol 17, Num 2, pp 153-172, issn 0197-4580, 19 p.Article

Heparin promotes β-secretase cleavage of the Alzheimer's amyloid precursor proteinLEVEUGLE, B; DING, W; DURKIN, J. T et al.Neurochemistry international. 1997, Vol 30, Num 6, pp 543-548, issn 0197-0186Article

Comment on: Mutant and native human β-amyloid precursor proteins in transgenic mouse brain. Authors' replyHOWLAND, D. S; SAVAGE, M. J; SWANSON, M. E et al.Neurobiology of aging. 1995, Vol 16, Num 4, pp 685-718, issn 0197-4580, 30 p.Article

Proteolytic processing of β-amyloid precursor by calpain ISIMAN, R; CARD, J. P; DAVIS, L. G et al.The Journal of neuroscience. 1990, Vol 10, Num 7, pp 2400-2411, issn 0270-6474, 12 p.Article

Regulation of glutamate receptor binding by the cytoskeletal protein fodrinSIMAN, R; BAUDRY, M; LYNCH, G et al.Nature (London). 1985, Vol 313, Num 5999, pp 225-228, issn 0028-0836Article

Brain fodrin: substrate for calpain I, an endogenous calcium-activated proteaseSIMAN, R; BAUDRY, M; LYNCH, G et al.Proceedings of the National Academy of Sciences of the United States of America. Biological sciences. 1984, Vol 81, Num 11, pp 3572-3576, issn 0273-1134Article

Purification from synaptosomal plasma membranes of calpain I, a thiol protease activated by micromolar calcium concentrationsSIMAN, R; BAUDRY, M; LYNCH, G et al.Journal of neurochemistry. 1983, Vol 41, Num 4, pp 950-956, issn 0022-3042Article

Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damageSIMAN, R; NOSZEK, J. C; KEGERISE, C et al.The Journal of neuroscience. 1989, Vol 9, Num 5, pp 1579-1590, issn 0270-6474, 12 p.Article

Ontogeny, compartmentation, and turnover of spectrin isoforms in rat central neuronsSIMAN, R; MEHRDAD AHDOOT; LYNCH, G et al.The Journal of neuroscience. 1987, Vol 7, Num 1, pp 55-64, issn 0270-6474Article

Cyclosporin A limits calcium-induced axonal damage following traumatic brain injuryOKONKWO, D. O; BÜKI, A; SIMAN, R et al.Neuroreport (Oxford). 1999, Vol 10, Num 2, pp 353-358, issn 0959-4965Article

Nonpeptidic inhibitors of recombinant human calpain ICHATTERJEE, S; SENADHI, S; BOZYCZKO-COYNE, D et al.Bioorganic & medicinal chemistry letters (Print). 1997, Vol 7, Num 3, pp 287-290, issn 0960-894XArticle

The calcium-activated protease calpain I and ischemia-induced neurodegeneration. DiscussionSIMAN, R; BOZYCZKO-COYNE, D; SAVAGE, M. J et al.Advances in neurology. 1996, Vol 71, pp 167-175, issn 0091-3952Article

Cathepsin G : localization in human cerebral cortex and generation of amyloidogenic fragments from the β-amyloid precursor proteinSAVAGE, M. J; IQBAL, M; LOH, T et al.Neuroscience. 1994, Vol 60, Num 3, pp 607-619, issn 0306-4522Article

Identification of a metalloprotease from Alzheimer's disease brain able to degrade the β-amyloid precursor protein and generate amyloidogenic fragmentsPAPASTOITSIS, G; SIMAN, R; SCOTT, R et al.Biochemistry (Easton). 1994, Vol 33, Num 1, pp 192-199, issn 0006-2960Article

Processing of the β-amyloid precursor : multiple proteases generate and degrade potentially amyloidogenic fragmentsSIMAN, R; MISTRETTA, S; DURKIN, J. T et al.The Journal of biological chemistry (Print). 1993, Vol 268, Num 22, pp 16602-16609, issn 0021-9258Article

Prolonged calpain-mediated spectrin breakdown occurs regionally following experimental brain injury in the ratSAATMAN, K. E; BOZYCZKO-COYNE, D; MARCY, V et al.Journal of neuropathology and experimental neurology. 1996, Vol 55, Num 7, pp 850-860, issn 0022-3069Article

Regional distribution and time-course of calpain activation following kainate-induced activity in adult rat brainBI, X; CHANG, V; SIMAN, R et al.Brain research. 1996, Vol 726, Num 1-2, pp 98-108, issn 0006-8993Article

P₂-ACHIRAL, P'-extended α-ketoamide inhibitors of calpain ICHATTERJEE, S; DUNN, D; MING TAO et al.Bioorganic & medicinal chemistry letters (Print). 1999, Vol 9, Num 16, pp 2371-2374, issn 0960-894XArticle